KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRIK3
All Species:
26.67
Human Site:
S158
Identified Species:
53.33
UniProt:
Q13003
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13003
NP_000822.2
919
104037
S158
N
L
Y
P
D
Y
A
S
L
S
H
A
I
L
D
Chimpanzee
Pan troglodytes
Q5IS46
956
107246
D145
N
L
H
P
S
N
T
D
I
S
V
A
V
A
G
Rhesus Macaque
Macaca mulatta
XP_001111351
919
103944
S158
N
L
Y
P
D
Y
A
S
L
S
H
A
I
L
D
Dog
Lupus familis
XP_850331
919
104085
S158
N
L
Y
P
D
Y
A
S
L
S
H
A
I
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P39087
908
102468
S155
S
L
Y
P
D
F
S
S
L
S
R
A
I
L
D
Rat
Rattus norvegicus
P42264
919
104053
S158
N
L
Y
P
D
Y
A
S
L
S
H
A
I
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510480
912
102862
S158
N
L
Y
P
D
Y
A
S
L
S
H
A
I
L
D
Chicken
Gallus gallus
P19439
487
54337
Frog
Xenopus laevis
Q91755
285
32023
Zebra Danio
Brachydanio rerio
XP_690040
906
102334
S183
N
L
Y
P
D
Y
A
S
I
S
R
A
V
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03445
991
111650
D154
F
A
I
S
M
R
P
D
Y
H
Q
A
I
I
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34299
962
108124
L166
H
K
G
W
G
E
V
L
V
L
I
D
P
V
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.6
99.5
99
N.A.
78.2
98.6
N.A.
93.3
22.6
24.4
69
N.A.
31.8
N.A.
31.5
N.A.
Protein Similarity:
100
59.5
99.7
99.6
N.A.
88.4
99.3
N.A.
96.5
35.5
28.7
82.5
N.A.
52.4
N.A.
50.4
N.A.
P-Site Identity:
100
33.3
100
100
N.A.
73.3
100
N.A.
100
0
0
80
N.A.
20
N.A.
0
N.A.
P-Site Similarity:
100
53.3
100
100
N.A.
93.3
100
N.A.
100
0
0
93.3
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
50
0
0
0
0
75
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
59
0
0
17
0
0
0
9
0
0
67
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
9
% G
% His:
9
0
9
0
0
0
0
0
0
9
42
0
0
0
9
% H
% Ile:
0
0
9
0
0
0
0
0
17
0
9
0
59
9
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
67
0
0
0
0
0
9
50
9
0
0
0
59
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
59
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
67
0
0
9
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
17
0
0
0
0
% R
% Ser:
9
0
0
9
9
0
9
59
0
67
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
9
0
9
0
17
9
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
59
0
0
50
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _